Histoplasmose gedissemineerd

Advices

≥ 18 years
Priority Medication Remarks
Priority:
1st choice
Medication:

ambisome iv 3mg/kg 1dd

Remarks:

Indien CNS betrokkenheid dosering ophogen naar 5mg/kg 1dd.

Priority:
2nd choice
Medication:

itraconazol po loading dose 800mg, 200mg 2dd

General comments

Bij goede respons na 2 weken overgaan op itraconazol po 200mg 2 dd, itraconazol spiegels bepalen (apotheek).

Totale duur van de behandeling 1 jaar mits CD4 langer dan 6 maanden > 150 zijn.

In alle andere gevallen doorgaan met secundaire profylaxe: itraconazol 200mg 1 dd. 

Sources

  1. Pubmed.gov publication # 17806045

    IDSA treatment guidelines: Clin Infect Dis 45;807,2007

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
Menu position
Metadata

Swab vid: G-461677.3
Updated: 06/18/2020 - 12:08
Status: Published