Pneumocystis jirovecii Pneumonie (PJP)

Advices

≥ 18 years
Priority Medication Remarks
Medication:

Cotrimoxazol (sulfamethoxazol + trimethoprim) iv 1920mg 3dd 14 days

Remarks:

Indien mogelijk behandeling per os

Medication:

Cotrimoxazol (sulfamethoxazol + trimethoprim) iv 1440mg 3dd 14 days

Remarks:

gewicht < 50 kg, indien mogelijk behandeling per os

Medication:

trimethoprim po 300mg 3dd 21 days

+

dapsone po 100mg 1dd 21 days

Remarks:

overgevoeligheid co-trimoxazol

Medication:

Clindamycine iv 600mg 3dd 21 days

+

primaquine po 30mg 1dd 21 days

Remarks:

overgevoeligheid co-trimoxazol

Indien mogelijk clindamycine per os

 

Medication:

atovaquon po 750mg 2dd 21 days

Remarks:

suspensie, innemen met voedsel; alleen bij niet ernstige PCP

Medication:

pentamidine iv 4mg/kg 1dd 21 days

Remarks:

laatste lijn

General comments

Bij pO2 < 70 mm Hg of 8-9 kPa toevoegen prednison:

dag 1-5 2 dd 40 mg;
dag 6-10 2 dd 20 mg;
dag 11-14 1 dd 20 mg

Na behandeling secundaire profylaxe

Sources

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-463567.4
Updated: 07/16/2020 - 15:45
Status: Published