Appendicitis - met chirurgie
Advices
| Priority | Medication | Remarks | 
|---|---|---|
| Priority: 1st choice | 
                          Remarks: 
                           Bij primair chirurgische behandeling geen antibiotica bij ongecompliceerde appendicitis. | |
| Priority: 1st choice alternative | Medication: Ceftriaxon iv 2000mg 1dd + Metronidazol iv 500mg 3dd | 
                          Remarks: 
                           Bij perforatie of gangreneuze appendicitis. Eventueel iv-orale switch na 48 uur. | 
| Priority: 1st choice alternative | Medication: Cotrimoxazol (sulfamethoxazol + trimethoprim) po 960mg 2dd + Metronidazol po 500mg 3dd | 
                          Remarks: 
                           Orale alternatieven | 
| Priority: 2nd choice alternative | Medication: Ciprofloxacine po 500mg 2dd + Metronidazol po 500mg 3dd | 
                          Remarks: 
                           Orale alternatieven | 
Sources
- 
          
                          Pubmed.gov publication # 36669519
              
              
            
                          2 days versus 5 days of postoperative antibiotics for complex appendicitis: a pragmatic, open-label, multicentre, non-inferiority randomised trial 
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
Menu position
Metadata
            Swab vid: G-462537.6
            Updated: 01/31/2025 - 17:10
            Status: Published
          
 
          
General comments
2 dagen postoperatieve (intraveneuze) antibiotica bij complexe appendicitis is niet minder effectief dan 5 dagen. Behandel alleen kritiek zieke patiënten 5 dagen postoperatief.