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Appendicitis - met chirurgie

Advices

≥ 18 years

Indications: appendicitis met operatieve ingreep

Priority Medication Remarks
Priority:
1st choice
Remarks:

Bij primair chirurgische behandeling geen antibiotica bij ongecompliceerde appendicitis.

Priority:
1st choice alternative
Medication:

Ceftriaxon iv 2000mg 1dd

+

Metronidazol iv 500mg 3dd

Remarks:

Bij perforatie of gangreneuze appendicitis. Eventueel iv-orale switch na 48 uur.

Priority:
1st choice alternative
Medication:

Cotrimoxazol (sulfamethoxazol + trimethoprim) po 960mg 2dd

+

Metronidazol po 500mg 3dd

Remarks:

Orale alternatieven

Priority:
2nd choice alternative
Medication:

Ciprofloxacine po 500mg 2dd

+

Metronidazol po 500mg 3dd

Remarks:

Orale alternatieven

General comments

2 dagen postoperatieve (intraveneuze) antibiotica bij complexe appendicitis is niet minder effectief dan 5 dagen. Behandel alleen kritiek zieke patiënten 5 dagen postoperatief.

Sources

  1. Pubmed.gov publication # 36669519

    2 days versus 5 days of postoperative antibiotics for complex appendicitis: a pragmatic, open-label, multicentre, non-inferiority randomised trial

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-462537.6
Updated: 01/31/2025 - 17:10
Status: Published