pyrazinamide
J - Antiinfectives For Systemic Use -> J04 - Antimycobacterials -> J04A - Drugs For Treatment Of Tuberculosis -> J04AK - Other Drugs For Treatment Of Tuberculosis -> J04AK01 - Pyrazinamide
Administration category:
Free
Medicine group:
antibacterial
Safety margins
| Weight | ROA | Dosage |
|---|---|---|
|
ROA: po |
Dosage: min. 30mg/kg 1 dd to max. 50mg/kg 1 dd |
|
|
ROA: po |
Dosage: to max. 2g/24h in 1 doses |
Kidney function
| ROA | GFR | Dosage | Interval | Comments |
|---|---|---|---|---|
| ROA: po | ||||
|
GFR: <30 |
Dosage: standaarddosering 3x per week, max. 2 g per keer, op geleide van de spiegel |
|||
Renal elimination:
4-14%
Dosage:
dependent on kidney function
Renal function-replacement therapy
CAPD: standaarddosering 3x per week, op geleide van de spiegel
Hemo dialysis: standaarddosering 3x per week, max. 2 g per keer, op geleide van de spiegel; bij hemodialyse toedienen na de dialyse
CAV / VVHD: doseren op geleide van de spiegel
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-1711.2
Updated: 10/15/2021 - 12:16
Status: Published