Rifampicine

J - Antiinfectives For Systemic Use -> J04 - Antimycobacterials -> J04A - Drugs For Treatment Of Tuberculosis -> J04AB - Antibiotics -> J04AB02 - Rifampicin
Administration category: Free Medicine group: antibacterial

Standard dosages

≥ 18 years
WeightROALoadDosage
< 50 kg
ROA:
po
Load:
-
Dosage:
450mg 1 dd
ROA:
iv
Load:
-
Dosage:
450mg 1 dd
Comments:

zo nodig 450 mg 2 dd.

≥ 50 kg
ROA:
po
Load:
-
Dosage:
600mg 1 dd
ROA:
iv
Load:
-
Dosage:
600mg 1 dd
Comments:

zo nodig 600 mg 2 dd. Bij obesitas is dosering aanpassing niet nodig, zie https://amsterdamumc.adult.swabid.nl/node/497959

Kidney function

Renal elimination: 6-15%
Dosage: independent on kidney function

Interactions

Interaction with (ATC): Expected effect:
Interaction with (ATC):
L04AD01 - Ciclosporin
Expected effect:
verlaagde ciclosporineconcentratie in volbloed
Interaction with (ATC):
C01BA03 - Disopyramide
Expected effect:
verlaging plasmaconcentratie disopyramide
Interaction with (ATC):
J01AA02 - Doxycycline
Expected effect:
verlaging plasmaconcentratie doxycycline
Interaction with (ATC):
N03AB02 - Phenytoin
Expected effect:
verlaging plasmaconcentratie fenytoine
Interaction with (ATC):
J02AC - Triazole Derivatives
Expected effect:
verlaging plasmaconcentratie –azolen en verhoging plasmaconcentratie rifampicine
Interaction with (ATC):
N03AX09 - Lamotrigine
Expected effect:
afname werkzaamheid lamotrigine
Interaction with (ATC):
B01AA - Vitamin K Antagonists
Expected effect:
verminderd effect orale anticoagulantia
Interaction with (ATC):
J05AE - Protease Inhibitors
Expected effect:
zeer sterke daling concentratie proteaseremmer
Interaction with (ATC):
L04AA10 - Sirolimus
Expected effect:
verlaging plasmaconcentratie sirolimus
Interaction with (ATC):
L04AD02 - Tacrolimus
Expected effect:
verlaging plasmaconcentratie tacrolimus
Interaction with (ATC):
G03A - Hormonal Contraceptives For Systemic Use
Expected effect:
verminderd effect orale anticonceptiva

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-500191.1
Updated: 03/23/2021 - 15:33
Status: Published

External links
Menu position